Yazar "Tiruchinapally, Gopinath" için listeleme
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Formulation of acid-sensitive micelles for delivery of cabazitaxel into prostate cancer cells
Aydın, Ömer; Youssef, İbrahim; Durmaz Yüksel, Yasemin; Tiruchinapally, Gopinath; ElSayed, Mohamed E. H. (Amer Chemical Soc, 2016)We report the synthesis of an amphiphilic triblock copolymer composed of a hydrophilic polyethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a hydrophobic poly(methyl methacrylate) (PMMA) block ... -
Selective binding of pVTK peptide-and bisphosphonate-functionalized micelles to prostate cancer cells, osteoblasts, and osteoclasts
Aydın, Ömer; Tiruchinapally, Gopinath; Youssef, Ibrahim; Ramaraju, Harsha; Yüksel Durmaz, Yasemin; Kozloff, Kenneth M.; Kohn, David H.; Elsayed, Mohamed E. H. (Andover House, Inc., 2022)This report describes the development of functionalized polymeric micelles encapsulating a chemotherapeutic agent. The results indicate the ability to achieve selective uptake into different cell populations in metastatic ... -
Synergistic inhibition of aggressive breast cancer cell migration and invasion by cytoplasmic delivery of anti-RhoC silencing RNA and presentation of EPPT1 peptide on "smart" particles
Kaushal, Neha; Tiruchinapally, Gopinath; Yüksel Durmaz, Yasemin; Bao, Liwei; Gilani, Rabia; Merajver, Sofia D.; ElSayed, Mohamed E. H. (Elsevier Science Bv, 2018)Overexpression of RhoC protein in breast cancer patients has been linked to increased cancer cell invasion, migration, and metastases. Suppressing RhoC expression in aggressive breast cancer cells using silencing RNA (siRNA) ...